PRECISION MEDICINE AND LIFESTYLE MEDICINE: PATHWAYS TOWARDS PERSONALIZED HEALTHCARE
DOI:
https://doi.org/10.47180/omij.v6i1.388Keywords:
Precision Medicine, Lifestyle Medicine, Genetics,, Chronic Disease Prevention,, Personalized Healthcare.Abstract
Este estudio tuvo como objetivo analizar las contribuciones de esta integración a la prevención, el manejo y la reversión de las enfermedades crónicas, además de identificar los desafíos éticos, económicos y sociales relacionados con su implementación. Mediante una investigación bibliográfica exploratoria y descriptiva, se analizaron publicaciones científicas de bases de datos nacionales e internacionales, seleccionadas con base en criterios de relevancia, actualidad y calidad metodológica. Los resultados indicaron que la Medicina de Precisión, al incorporar datos genéticos, epigenéticos, ambientales y conductuales, potencia la efectividad de las intervenciones propuestas por la Medicina del Estilo de Vida. Esta sinergia permite diagnósticos más asertivos, tratamientos personalizados y estrategias de prevención proactivas, reduciendo las complicaciones y optimizando los recursos sanitarios.
Downloads
References
APALASAMY, Y. D.; MOHAMED, Z. Obesity and genomics: role of technology in unraveling the complex genetic architecture of obesity. Human Genetics, v. 134, n. 4, p. 361-374, 2015. DOI: 10.1007/S00439-015-1533-X.
CHEN, X. Analyses and concerns in precision medicine: A statistical perspective. ArXiv, 2024. DOI: 10.48550/arxiv.2401.06899.
GRAY, S. G. et al. Precision lifestyle medicine: A new frontier for chronic disease prevention. American Journal of Lifestyle Medicine, v. 14, n. 2, p. 115-130, 2020. DOI: 10.1177/1559827619884466.
IRIART, J. A. B. Precision medicine/personalized medicine: a critical analysis of movements in the transformation of biomedicine in the early 21st century. Cadernos de Saúde Pública, v. 35, n. 3, p. 1-11, 2019. DOI: 10.1590/0102-311X00153118.
KATZ, D. L. et al. Lifestyle as medicine: The case for a true health initiative. American Journal of Health Promotion, v. 32, n. 6, p. 1452-1458, 2018. DOI: 10.1177/0890117117705949.
MALLIN, M. et al. A pilot retrospective study of a physician-directed and genomics-based model for precision lifestyle medicine. Frontiers in Medicine, v. 10, p. 1239737, 2023. DOI: 10.3389/fmed.2023.1239737.
MCNEIL, D. W.; ADDICKS, S. H.; RANDALL, C. L. Motivational interviewing and motivational interactions for health behavior change and maintenance. Oxford: Oxford University Press, 2017.
MONDA, V. et al. Exercise modifies the gut microbiota with positive health effects. Oxidative Medicine and Cellular Longevity, v. 2017, p. 3831972, 2017. DOI: 10.1155/2017/3831972.
MOOSAVI, A.; ARDEKANI, A. M. Role of epigenetics in biology and human diseases. Iranian Biomedical Journal, v. 20, n. 5, p. 246-258, 2016. DOI: 10.22045/IBJ.2016.01.
NEDAEINIA, R. et al. Lifestyle genomic interactions in health and disease. Springer, p. 25-74, 2021. DOI: 10.1007/978-3-030-85357-0_3.
NAKAMURA, S. et al. Effects of gene-lifestyle interactions on obesity based on a multi-locus risk score: A cross-sectional analysis. PLOS ONE, v. 18, n. 2, p. e0279169, 2023. DOI: 10.1371/journal.pone.0279169.
RAMASWAMY, G. Precision medicine and public health practice. Elsevier, p. 273-286, 2024. DOI: 10.1016/b978-0-323-95356-6.00006-9.
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Open Minds International Journal

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The authors declare that any work submitted, if accepted, will not be published elsewhere, in English or in any other language, and even electronically, unless it expressly mentions that the work was originally published in the Journal.










