MEDICINA DE PRECISIÓN Y MEDICINA DEL ESTILO DE VIDA: CAMINOS HACIA LA ATENCIÓN MÉDICA PERSONALIZADA
DOI:
https://doi.org/10.47180/omij.v6i1.388Palabras clave:
Medicina de Precisión,, Medicina del Estilo de Vida,, Genética,, Prevención de Enfermedades Crónica, Atención Médica Personalizada.Resumen
he growing prevalence of chronic non-communicable diseases has driven the search for innovative prevention and treatment strategies that consider the individuality of each patient. In this context, the integration of Precision Medicine and Lifestyle Medicine emerges as a promising approach, capable of offering personalized and effective interventions. This study aimed to analyze the contributions of this integration to the prevention, management, and reversal of chronic conditions, in addition to identifying ethical, economic, and social challenges related to its implementation. Through exploratory and descriptive bibliographic research, scientific publications from national and international databases were analyzed, selected based on criteria of relevance, timeliness, and methodological quality. The results indicated that Precision Medicine, by incorporating genetic, epigenetic, environmental, and behavioral data, enhances the effectiveness of interventions proposed by Lifestyle Medicine. This synergy enables more assertive diagnoses, personalized treatments, and proactive prevention strategies, reducing complications and optimizing healthcare resources.
Descargas
Referencias
APALASAMY, Y. D.; MOHAMED, Z. Obesity and genomics: role of technology in unraveling the complex genetic architecture of obesity. Human Genetics, v. 134, n. 4, p. 361-374, 2015. DOI: 10.1007/S00439-015-1533-X.
CHEN, X. Analyses and concerns in precision medicine: A statistical perspective. ArXiv, 2024. DOI: 10.48550/arxiv.2401.06899.
GRAY, S. G. et al. Precision lifestyle medicine: A new frontier for chronic disease prevention. American Journal of Lifestyle Medicine, v. 14, n. 2, p. 115-130, 2020. DOI: 10.1177/1559827619884466.
IRIART, J. A. B. Precision medicine/personalized medicine: a critical analysis of movements in the transformation of biomedicine in the early 21st century. Cadernos de Saúde Pública, v. 35, n. 3, p. 1-11, 2019. DOI: 10.1590/0102-311X00153118.
KATZ, D. L. et al. Lifestyle as medicine: The case for a true health initiative. American Journal of Health Promotion, v. 32, n. 6, p. 1452-1458, 2018. DOI: 10.1177/0890117117705949.
MALLIN, M. et al. A pilot retrospective study of a physician-directed and genomics-based model for precision lifestyle medicine. Frontiers in Medicine, v. 10, p. 1239737, 2023. DOI: 10.3389/fmed.2023.1239737.
MCNEIL, D. W.; ADDICKS, S. H.; RANDALL, C. L. Motivational interviewing and motivational interactions for health behavior change and maintenance. Oxford: Oxford University Press, 2017.
MONDA, V. et al. Exercise modifies the gut microbiota with positive health effects. Oxidative Medicine and Cellular Longevity, v. 2017, p. 3831972, 2017. DOI: 10.1155/2017/3831972.
MOOSAVI, A.; ARDEKANI, A. M. Role of epigenetics in biology and human diseases. Iranian Biomedical Journal, v. 20, n. 5, p. 246-258, 2016. DOI: 10.22045/IBJ.2016.01.
NEDAEINIA, R. et al. Lifestyle genomic interactions in health and disease. Springer, p. 25-74, 2021. DOI: 10.1007/978-3-030-85357-0_3.
NAKAMURA, S. et al. Effects of gene-lifestyle interactions on obesity based on a multi-locus risk score: A cross-sectional analysis. PLOS ONE, v. 18, n. 2, p. e0279169, 2023. DOI: 10.1371/journal.pone.0279169.
RAMASWAMY, G. Precision medicine and public health practice. Elsevier, p. 273-286, 2024. DOI: 10.1016/b978-0-323-95356-6.00006-9.
Descargas
Publicado
Número
Sección
Licencia
Derechos de autor 2025 Open Minds International Journal
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.
Los autores declaran que cualquier trabajo presentado, si se acepta, no se publicará en otro lugar, en inglés o en cualquier otro idioma, e incluso electrónicamente, a menos que mencione expresamente que el trabajo se publicó originalmente en la revista.
